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伴刀豆球蛋白A中金属离子丢失的流体动力学变化

Hydrodynamic changes accompanying the loss of metal ions from concanavalin A.

作者信息

Sawyer H W, Dabscheck R, Nott P R, Selinger B K, Kuntz I D

出版信息

Biochem J. 1975 Jun;147(3):613-5. doi: 10.1042/bj1470613.

Abstract

The hydrodynamic changes which accompany the dissociation of metal ions, from concanavalin A at acid pH are a result of charge effects rather than of dissociation of metal ions as such. Measurements of the rotational relaxation time are discussed in terms of the hydration of the protein and its polymeric heterogeneity.

摘要

在酸性pH条件下,伴刀豆球蛋白A中金属离子解离所伴随的流体动力学变化是电荷效应的结果,而非金属离子本身的解离。根据蛋白质的水合作用及其聚合物异质性对旋转弛豫时间的测量进行了讨论。

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本文引用的文献

3
Ultraviolet difference spectral studies on concanavalin A. Carbohydrate interaction.
Eur J Biochem. 1970 Nov;16(3):549-56. doi: 10.1111/j.1432-1033.1970.tb01116.x.
4
Conformational changes in concanavalin A.
J Biol Chem. 1971 Jul 10;246(13):4369-70.
5
The molecular weight and stability of concanavalin A.
Biochim Biophys Acta. 1972 Apr 15;263(2):283-93. doi: 10.1016/0005-2795(72)90081-5.
9
Hydration of proteins and polypeptides.蛋白质和多肽的水合作用。
Adv Protein Chem. 1974;28:239-345. doi: 10.1016/s0065-3233(08)60232-6.
10
The covalent and three-dimensional structure of concanavalin A.伴刀豆球蛋白A的共价和三维结构
Proc Natl Acad Sci U S A. 1972 Sep;69(9):2580-4. doi: 10.1073/pnas.69.9.2580.

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