Sawyer H W, Dabscheck R, Nott P R, Selinger B K, Kuntz I D
Biochem J. 1975 Jun;147(3):613-5. doi: 10.1042/bj1470613.
The hydrodynamic changes which accompany the dissociation of metal ions, from concanavalin A at acid pH are a result of charge effects rather than of dissociation of metal ions as such. Measurements of the rotational relaxation time are discussed in terms of the hydration of the protein and its polymeric heterogeneity.
在酸性pH条件下,伴刀豆球蛋白A中金属离子解离所伴随的流体动力学变化是电荷效应的结果,而非金属离子本身的解离。根据蛋白质的水合作用及其聚合物异质性对旋转弛豫时间的测量进行了讨论。