Zhumatov K Kh, Kosiakov P N
Vopr Virusol. 1985 May-Jun;30(3):302-7.
The immunogenic activity of antigenic determinants of influenza type B viruses in primary and booster immunizations was studied. In primary immunization, the highest immunogenicity was found with the type- and strain-specific antigenic determinants whereas the antigenic determinants of group specificity were less immunogenic. After booster immunizations the animal sera had antibody to all 3 antigenic determinants.
研究了乙型流感病毒抗原决定簇在初次免疫和加强免疫中的免疫原性活性。在初次免疫中,发现型特异性和株特异性抗原决定簇具有最高的免疫原性,而组特异性抗原决定簇的免疫原性较低。加强免疫后,动物血清对所有三种抗原决定簇均产生了抗体。