Department of Biology and Biocenter Oulu, University of Oulu, FIN-90014 Oulu, Finland.
Nat Rev Genet. 2013 Nov;14(11):807-20. doi: 10.1038/nrg3522.
It is increasingly important to improve our understanding of the genetic basis of local adaptation because of its relevance to climate change, crop and animal production, and conservation of genetic resources. Phenotypic patterns that are generated by spatially varying selection have long been observed, and both genetic mapping and field experiments provided initial insights into the genetic architecture of adaptive traits. Genomic tools are now allowing genome-wide studies, and recent theoretical advances can help to design research strategies that combine genomics and field experiments to examine the genetics of local adaptation. These advances are also allowing research in non-model species, the adaptation patterns of which may differ from those of traditional model species.
由于其与气候变化、作物和动物生产以及遗传资源保护的相关性,提高我们对本地适应遗传基础的理解变得越来越重要。由空间变化选择产生的表型模式很早就被观察到了,遗传图谱和田间试验都为适应性特征的遗传结构提供了初步的见解。基因组工具现在允许进行全基因组研究,最近的理论进展可以帮助设计结合基因组学和田间试验的研究策略,以研究本地适应的遗传学。这些进展还使非模式物种的研究成为可能,其适应模式可能与传统模式物种的适应模式不同。