Choi Sharon S, Mehran Roxana
The Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Expert Rev Cardiovasc Ther. 2013 Oct;11(10):1337-47. doi: 10.1586/14779072.2013.839190.
This review aims to describe new developments in coronary revascularization strategies for patients with pre-existing Type 2 diabetes mellitus (DM). Recommended strategies for revascularization have been an active area of study with recent important developments. In patients with Type 2 DM and multivessel coronary artery disease (CAD), coronary artery bypass graft (CABG) surgery is the preferred method for revascularization. Patients with DM are at increased risk for diffuse cardiovascular disease due to the proinflammatory, prothrombotic effects of chronic hyperglycemia. In patients undergoing percutaneous coronary intervention, drug-eluting stents and more potent antiplatelet agents especially in those presenting with acute coronary syndromes should be employed.
本综述旨在描述已有2型糖尿病(DM)患者冠状动脉血运重建策略的新进展。血运重建的推荐策略一直是一个积极的研究领域,近期有重要进展。在患有2型糖尿病和多支冠状动脉疾病(CAD)的患者中,冠状动脉旁路移植术(CABG)是血运重建的首选方法。由于慢性高血糖的促炎、促血栓形成作用,糖尿病患者发生弥漫性心血管疾病的风险增加。在接受经皮冠状动脉介入治疗的患者中,应使用药物洗脱支架和更强效的抗血小板药物,尤其是在那些患有急性冠状动脉综合征的患者中。