University of North Dakota, Grand Forks, ND, USA.
Physiol Behav. 2014 Jan 17;123:100-4. doi: 10.1016/j.physbeh.2013.10.001. Epub 2013 Oct 18.
Ames dwarf mice have an extended lifespan by comparison with normal mice. Behavioral testing has revealed that sometimes Ames dwarf mice also evince superior performances relative to normal mice, but in other cases they do not. In this experiment, Ames dwarf and normal mice were compared on a T-maze test and on a delayed nonmatching-to-sample variant of a T-maze test. On the simple T-maze, Ames dwarf and normal mice committed comparable numbers of errors. On the nonmatching-to-sample task, normal mice mastered the discrimination by the end of the experiment while Ames dwarf mice did not. The apparatus, distances traveled and session duration were equivalent between the two tasks. The poorer performances of Ames dwarf mice on the nonmatching-to-sample task suggests that Ames dwarf mice may not be as capable of learning relatively cognitively complex tasks as normal mice.
与正常老鼠相比，艾姆斯矮鼠的寿命更长。行为测试表明，艾姆斯矮鼠有时相对于正常老鼠表现出更好的性能，但在其他情况下并非如此。在这项实验中，艾姆斯矮鼠和正常老鼠在 T 迷宫测试和 T 迷宫的延迟非匹配样本变体测试上进行了比较。在简单的 T 迷宫中，艾姆斯矮鼠和正常老鼠犯的错误数量相当。在非匹配样本任务中，正常老鼠在实验结束时掌握了辨别能力，而艾姆斯矮鼠则没有。在两个任务中，仪器、行进距离和会话持续时间都是相等的。艾姆斯矮鼠在非匹配样本任务上表现较差，这表明艾姆斯矮鼠在学习相对认知复杂任务方面可能不如正常老鼠。
