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年轻患者的巨细胞动脉炎。

Temporal arteritis in a young patient.

机构信息

Kayseri Education and Research Hospital, Department of Internal Medicine, Kayseri, Turkey.

出版信息

Clin Exp Rheumatol. 2014 May-Jun;32(3 Suppl 82):S59-61. Epub 2013 Oct 17.

Abstract

Temporal arteritis in the young is clinically and histologically different from classic giant cell arteritis of the elderly population. A male patient, aged 36 years, presented with headache and a nodule in his left temporal region. Histological examination of the nodule showed that the left temporal artery was encircled by a lymphoid tissue with prominent germinal centres. The arterial wall was infiltrated with mixed inflammatory cells, the internal elastic lamina was disrupted, and there was marked intimal hyperplasia. The patient was diagnosed with juvenile temporal arteritis. Because of persistent headache after surgical excision of the lesion, the patient was treated with prednisolone. Systemic vasculitides, classic giant cell arteritis, Kimura's disease, and angiolymphoid hyperplasia with eosinophilia should be considered in the differential diagnosis of the disease.

摘要

年轻人的颞动脉炎在临床和组织学上与老年人的典型巨细胞动脉炎不同。一位 36 岁的男性患者,表现为头痛和左侧颞部的结节。结节的组织学检查显示,左侧颞动脉被一个具有明显生发中心的淋巴组织环绕。动脉壁浸润有混合性炎症细胞,内弹性膜破裂,内膜明显增生。该患者被诊断为青少年颞动脉炎。由于病变切除术后持续头痛,该患者接受泼尼松龙治疗。在鉴别诊断中应考虑到系统性血管炎、经典巨细胞动脉炎、Kimura 病和伴有嗜酸性粒细胞的血管淋巴样增生。

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