Fallahinejad Ghajari Masoud, Mirkarimi Mahkameh, Vatanpour Mehdi, Kharrazi Fard Mohammad Javad
Department of Pediatric Dentistry, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Iran Endod J. 2008 Summer;3(3):45-9. Epub 2008 Jul 10.
There are various studies looking at the effects of formocresol (FC) and mineral trioxide aggregate (MTA) on pulpotomy of primary molars. This is a systematic review of literature comparing the success rates of MTA and FC in pulpotomy of primary molars.
The study list was obtained using PubMed, EMBASE, Scopus, Science Citation Index, Iran Medex, Google Scholar, the Cochrane Library, and also some hand searches contains through dental journals approved by the Iranian Ministry of Health. Papers which met the inclusion were accepted. The quality of studies for the meta-analysis was assessed by a series of validity criteria according to Jadad's scale. Eight qualified studies met the criteria. Terms of clinical outcomes and radiographic findings were evaluated in all studies to assess clinical success and root resorption. Fixed model was applied to aggregate the data of homogenous studies. A random effect model was carried out for measuring the effect size of heterogeneous studies.
The overall clinical and radiographic success rates based on the data suggested that MTA was superior to FC (P=0.004) with the Odds Ratio=3.535 and 95% confidence interval (1.494-8.369).
Primary molars pulpotomy with MTA have better clinical and radiographic success rates than FC. (Iranian Endodontic Journal 2008;3:45-9).
有多项研究探讨了甲醛甲酚（FC）和矿物三氧化物凝聚体（MTA）对乳磨牙牙髓切断术的影响。这是一项系统的文献综述，比较了MTA和FC在乳磨牙牙髓切断术中的成功率。
通过PubMed、EMBASE、Scopus、科学引文索引、伊朗医学数据库、谷歌学术、考克兰图书馆获取研究列表，同时还通过伊朗卫生部批准的牙科期刊进行了一些手工检索。符合纳入标准的论文被接受。根据Jadad量表的一系列有效性标准评估纳入荟萃分析的研究质量。八项合格研究符合标准。在所有研究中评估临床结果和影像学表现的术语，以评估临床成功率和牙根吸收情况。应用固定模型汇总同质研究的数据。对异质研究采用随机效应模型测量效应量。
基于数据的总体临床和影像学成功率表明，MTA优于FC（P = 0.004），优势比为3.535，95%置信区间为（1.494 - 8.369）。
与FC相比，使用MTA进行乳磨牙牙髓切断术具有更好的临床和影像学成功率。（《伊朗牙髓病学杂志》2008年；3：45 - 9）
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