Peng Li, Ye Ling, Tan Hong, Zhou Xuedong
Department of Endodontics, Sichuan University, West China School of Dentistry, Chengdu, China.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Dec;102(6):e40-4. doi: 10.1016/j.tripleo.2006.05.017. Epub 2006 Sep 26.
To apply meta-analysis to compare the clinical and radiographic effects of mineral trioxide aggregate (MTA) with formocresol (FC) when used as wound dressing for pulpotomy of primary molars.
The study list was obtained by searching MEDLINE, The Cochrane Library, EMBASE, and SCI. Only those papers that met the inclusion criteria were analyzed.
Six studies met the inclusion criteria. There was significant difference between the success rates of FC- and MTA-treated pulpotomized primary molars (P < .05). Clinical assessments and radiographic findings of the MTA versus FC pulpotomy suggested that MTA was superior to FC in pulpotomy resulting in a lower failure rate, with the RR (Relative Risk) being 0.32 (95% confidence interval [CI] 0.11 to 0.90) and 0.31 (95% CI 0.13 to 0.74), respectively. Internal root resorption happened less in the MTA group with RR 0.29, 95% CI 0.11 to 0.77.
MTA induces less undesirable responses and might be FC's suitable replacement.
应用荟萃分析比较无机三氧化物聚合物（MTA）与甲醛甲酚（FC）作为乳牙活髓切断术伤口敷料时的临床和影像学效果。
通过检索MEDLINE、Cochrane图书馆、EMBASE和SCI获取研究列表。仅分析符合纳入标准的论文。
六项研究符合纳入标准。FC治疗组和MTA治疗组乳牙活髓切断术的成功率之间存在显著差异（P < 0.05）。MTA与FC活髓切断术的临床评估和影像学结果表明，MTA在活髓切断术中优于FC，失败率更低，相对危险度（RR）分别为0.32（95%置信区间[CI]0.11至0.90）和0.31（95%CI 0.13至0.74）。MTA组内吸收发生较少，RR为0.29，95%CI为0.11至0.77。
MTA引起的不良反应较少，可能是FC的合适替代品。
