Massoud Elsayed Ibraheem Elsayed
Elsayed Ibraheem Elsayed Massoud, Orthopaedic Department, Sohag Teaching Hospital, General Organization for Teaching Hospitals and Institutes, 82521 Tahta, Sohag, Egypt.
World J Orthop. 2013 Oct 18;4(4):229-40. doi: 10.5312/wjo.v4.i4.229.
Tendon ruptures remain a significant musculoskeletal injury. Despite advances in surgical techniques and procedures, traditional repair techniques maintain a high incidence of rerupture or tendon elongation. Mechanical loading and biochemical signaling both control tissue healing. This has led some researchers to consider using a technique based on tension regulation at the suture line for obtaining good healing. However, it is unknown how they interact and to what extent mechanics control biochemistry. This review will open the way for understanding the interplay between mechanical loading and the process of tendon healing.
肌腱断裂仍然是一种严重的肌肉骨骼损伤。尽管手术技术和操作有所进步,但传统的修复技术仍保持着较高的再断裂或肌腱延长发生率。机械负荷和生化信号都控制着组织愈合。这使得一些研究人员考虑使用一种基于缝线处张力调节的技术来实现良好的愈合。然而,它们如何相互作用以及力学在多大程度上控制生物化学尚不清楚。本综述将为理解机械负荷与肌腱愈合过程之间的相互作用开辟道路。