Jones C J, Ockleford C D
Placenta. 1985 Jul-Aug;6(4):355-61. doi: 10.1016/s0143-4004(85)80045-x.
In this study, the ultrastructure of the human placental 'nematosome' or 'glomerular body' is described. It is usually found as electron-dense aggregates forming an inclusion 0.3 to 0.5 micron in diameter and of variable length, and occurs within cytotrophoblast cells in different configurations which include spirals, concentric rings, parallel arrays, random coils and paracrystalline structures. Analysis of random electron micrographs of placentae from normal and complicated pregnancies showed that the nematosome is present in low frequencies in the first and second trimesters but is more commonly found at full term; their incidence did not differ markedly from normal in any of the pathological conditions studied, ranging from 10.4 to 21.9 per cent, and their frequency suggests that there may be several nematosomes per cell. The relationship of the nematosome to the centriole is discussed, and it is suggested that morphometric analysis may elucidate the three-dimensional structure of nematosomes, their distribution within cells and their relationship to the plasma and other membranes.
在本研究中，对人胎盘的“线虫样小体”或“肾小球样小体”的超微结构进行了描述。它通常表现为电子致密聚集体，形成直径0.3至0.5微米、长度可变的包涵体，并以不同形态出现在细胞滋养层细胞内，这些形态包括螺旋状、同心环、平行排列、随机卷曲和准晶体结构。对正常和复杂妊娠胎盘的随机电子显微镜照片分析表明，线虫样小体在妊娠早期和中期出现频率较低，但在足月时更常见；在所研究的任何病理情况下，其发生率与正常情况无明显差异，范围为10.4%至21.9%，其出现频率表明每个细胞可能有多个线虫样小体。讨论了线虫样小体与中心粒的关系，并提出形态计量分析可能有助于阐明线虫样小体的三维结构、它们在细胞内的分布以及它们与质膜和其他膜的关系。
