Brookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
Clin Ther. 2013 Nov;35(11):1659-68. doi: 10.1016/j.clinthera.2013.09.026. Epub 2013 Oct 19.
Chronic pain is prevalent among older adults but is underrecognized and undertreated. The approach to pain assessment and management in older adults requires an understanding of the physiology of aging, validated assessment tools, and common pain presentations among older adults.
To identify the overall principles of pain management in older adults with a specific focus on common painful conditions and approaches to pharmacologic treatment.
We searched PubMed for common pain presentations in older adults with heart failure, end-stage renal disease, dementia, frailty, and cancer. We also reviewed guidelines for pain management. Our review encompassed 2 guidelines, 10 original studies, and 22 review articles published from 2000 to the present. This review does not discuss nonpharmacologic treatments of pain.
Clinical guidelines support the use of opioids in persistent nonmalignant pain. Opioids should be used in patients with moderate or severe pain or pain not otherwise controlled but with careful attention to potential toxic effects and half-life. In addition, clinical practice guidelines recommend use of oral nonsteroidal anti-inflammatory drugs with extreme caution and for defined, limited periods.
An understanding of the basics of pain pathophysiology, assessment, pharmacologic management, and a familiarity with common pain presentations will allow clinicians to effectively manage pain for older adults.
慢性疼痛在老年人中很常见,但未得到充分认识和治疗。老年人疼痛评估和管理的方法需要了解衰老的生理学、经过验证的评估工具以及老年人常见的疼痛表现。
确定老年人疼痛管理的总体原则,特别关注老年人常见的疼痛病症和药物治疗方法。
我们在 PubMed 上搜索了心力衰竭、终末期肾病、痴呆、虚弱和癌症等老年人群中常见的疼痛表现。我们还回顾了疼痛管理指南。我们的综述包括 2 项指南、10 项原始研究和 22 篇综述文章,这些文章的发表时间均在 2000 年至目前。本综述不讨论疼痛的非药物治疗。
临床指南支持在持续性非恶性疼痛中使用阿片类药物。对于中度或重度疼痛或其他原因未得到控制的疼痛患者,应使用阿片类药物,但要密切注意潜在的毒性作用和半衰期。此外,临床实践指南建议谨慎使用口服非甾体抗炎药,并限定使用期限。
了解疼痛病理生理学、评估、药物管理的基础知识以及熟悉常见的疼痛表现将使临床医生能够有效管理老年人的疼痛。