Weber S
Z Erkr Atmungsorgane. 1985;165(1):3-12.
Monoclonal antibodies have been increasingly applied in medicine for diagnostic and therapeutic purposes instead of conventional antisera. In addition to their unlimited availability monoclonal antibodies have the advantage of defined specificity, affinity and of standard parameters. This paper describes the production of monoclonal antibodies using the hybridoma technique and surveys some potential fields of application such as infections, transplantations, tumours and lung diseases.
单克隆抗体已越来越多地应用于医学领域,用于诊断和治疗目的,而非传统抗血清。除了可无限供应外,单克隆抗体还具有特异性明确、亲和力高以及参数标准化的优势。本文描述了利用杂交瘤技术生产单克隆抗体的过程,并概述了一些潜在的应用领域,如感染、移植、肿瘤和肺部疾病。