Young W G
Acta Anat (Basel). 1985;123(2):131-6. doi: 10.1159/000146053.
Langerhans' cells were found to vary in their morphology and density in the vaginal epithelium of ovariectomized mice stimulated by single daily injections of oestrogen. In ATPase-stained epithelial sheet preparations, Langerhans' cells were small and stellate in dense distribution after ovariectomy produced epithelial atrophy. They became highly dendritic in sparse distribution as epithelial thickness increased with high mitotic activity. Keratinization when prolonged by daily oestrogen injections did not affect their morphology or distribution.
研究发现，在每日单次注射雌激素刺激的去卵巢小鼠阴道上皮中，朗格汉斯细胞的形态和密度存在差异。在ATP酶染色的上皮片层制剂中，去卵巢导致上皮萎缩后，朗格汉斯细胞体积小且呈星状，分布密集。随着上皮厚度因高有丝分裂活性而增加，它们变得高度树突状且分布稀疏。每日注射雌激素导致的角化延长并未影响它们的形态或分布。
