冠醚对非洲爪蟾有髓神经纤维离子电流的影响。
The effect of crown ethers on ionic currents in myelinated nerve fibres from Xenopus laevis.
作者信息
Kristbjarnarson H, Arhem P
出版信息
Acta Physiol Scand. 1985 Mar;123(3):261-8. doi: 10.1111/j.1748-1716.1985.tb07586.x.
Abstract
The effect of several crown ethers on the currents at the node of Ranvier was studied. At differing potencies they caused a time- and potential-dependent inactivation of potassium permeability and a time- and potential-independent decrease in sodium permeability. The relative effect on potassium and sodium systems varied and was not directly related to their ionophoric properties. A computer analysis indicated that the induced inactivation was dependent on the normal potassium activation mechanism.
摘要
研究了几种冠醚对郎飞结处电流的影响。它们在不同效力下引起钾通透性的时间和电位依赖性失活以及钠通透性的时间和电位非依赖性降低。对钾和钠系统的相对影响各不相同，且与它们的离子载体性质没有直接关系。计算机分析表明，诱导的失活依赖于正常的钾激活机制。
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