Tocci Giuliano, Borghi Claudio, Volpe Massimo
Division of Cardiology, Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, University of Rome "Sapienza", Sant'Andrea Hospital, Via di Grottarossa 1035-39, 00189, Rome, Italy,
High Blood Press Cardiovasc Prev. 2014 Jun;21(2):107-17. doi: 10.1007/s40292-013-0028-x. Epub 2013 Oct 23.
Hypertension management and control still represents a major clinical challenge for physicians, as well as for National Health Care Systems, since high blood pressure (BP) levels in treated uncontrolled outpatients are related to a persistently increased risk of cardiovascular (CV) events. The Italian Society of Hypertension (SIIA) has prompted several educational interventions for improving BP control in Italy.
To evaluate clinical attitudes and preferences of large community sample of both specialized physicians and general practitioners, included in an educational program, endorsed by SIIA and aimed at improving interventions for achieving better BP control in Italy.
A predefined questionnaire, which included a main body with 17 questions and 15 specific items (3-4 questions for each item), was anonymously administered to a large community sample of physicians who have practice in managing outpatients with hypertension and high CV risk profile. Both specialized physicians and general practitioners, distributed throughout the whole Italian territory, have been included in this educational program. Data were reported into a computerised spreadsheet and centrally analysed. Confidentiality of the data were guaranteed during each phase of the study.
From a total of 64 questions, 557 physicians (478 male, mean age 54.2 ± 7.1 years, average age of medical activity 28.0 ± 8.1 years), among which 261 (46.9 %) specialised physicians and 296 (53.1 %) general practitioners, provided 60,713 answers to the survey questionnaire. Physicians devote time and effort for achieving the recommended BP targets (<140/90 and <130/80 mmHg in high risk subgroups), yet they reported a very high rate of BP control (about 70 %). Concomitant presence of diabetes, cardiac and renal organ damage (35-50 %), as well as comorbidities (20-35 %), is reported to be high and able to impact on antihypertensive treatment's efficacy. Appropriate BP assessment is also viewed as a key tool for verifying effectiveness of a given drug therapy. Beyond non-pharmacological options, ACE inhibitors and ARBs were considered to most useful, effective and well tolerated options to start and maintain antihypertensive treatment, thus adding diuretics or calcium-channel blockers if needed. Direct renin inhibitors was considered to be effective in difficult to treat hypertension and to provide sustained antihypertensive efficacy.
With the well-known limitations of an observational, cross-sectional survey, in which a predefined questionnaire was administered to physicians rather than collecting data from medical databases, this study provides useful and updated information on attitudes and preferences, as well as on difficulties and troubles for physicians when managing outpatients with hypertension and high CV risk profile in Italy.
高血压的管理与控制对医生以及国家医疗保健系统而言仍是一项重大临床挑战,因为接受治疗但血压未得到控制的门诊患者的高血压水平与心血管(CV)事件风险持续增加相关。意大利高血压学会(SIIA)已推动多项教育干预措施以改善意大利的血压控制情况。
评估参与一项由SIIA认可的教育项目的专科医生和全科医生大型社区样本的临床态度和偏好,该项目旨在改进干预措施以在意大利实现更好的血压控制。
向大量从事高血压和高CV风险门诊患者管理工作的医生社区样本匿名发放一份预定义问卷,问卷主体包含17个问题和15个特定项目(每个项目3 - 4个问题)。分布在意大利全境的专科医生和全科医生均被纳入该教育项目。数据被录入计算机化电子表格并进行集中分析。在研究的每个阶段都保证了数据的保密性。
在总共64个问题中,557名医生(478名男性,平均年龄54.2±7.1岁,平均医疗活动年龄28.0±8.1岁)提供了60,713份调查问卷答案,其中261名(46.9%)为专科医生,296名(53.1%)为全科医生。医生们投入时间和精力来实现推荐的血压目标(高危亚组中<140/90 mmHg和<130/80 mmHg),然而他们报告的血压控制率非常高(约70%)。据报告,糖尿病、心脏和肾脏器官损害(35 - 50%)以及合并症(20 - 35%)的并存率较高,且会影响降压治疗的疗效。适当的血压评估也被视为验证特定药物治疗效果的关键工具。除了非药物选择外,血管紧张素转换酶抑制剂(ACE抑制剂)和血管紧张素Ⅱ受体拮抗剂(ARB)被认为是启动和维持降压治疗最有用、最有效且耐受性良好的选择,必要时可加用利尿剂或钙通道阻滞剂。直接肾素抑制剂被认为对难治性高血压有效,并能提供持续的降压效果。
尽管这项观察性横断面调查存在众所周知的局限性,即向医生发放预定义问卷而非从医疗数据库收集数据,但本研究提供了有关意大利医生在管理高血压和高CV风险门诊患者时的态度和偏好、困难与问题的有用且最新的信息。