Admiraal Wanda M, Holleman Frits, Hoekstra Joost B L
Academisch Medisch Centrum, afd. Inwendige Geneeskunde, Amsterdam.
Ned Tijdschr Geneeskd. 2013;157(43):A6813.
Weight loss is recommended for overweight or obese patients with type 2 diabetes on the basis of short-term studies, but the long-term effects of weight loss on cardiovascular disease are unknown. The recently published Look AHEAD (Action for health in diabetes) study investigated the 10-year effect of an intensive lifestyle intervention designed to achieve weight loss on cardiovascular morbidity and mortality among overweight or obese adults with type 2 diabetes. In this commentary, we discuss the results and clinical implications of this study.
基于短期研究，建议超重或肥胖的2型糖尿病患者进行减肥，但减肥对心血管疾病的长期影响尚不清楚。最近发表的“糖尿病健康行动（Look AHEAD）”研究调查了旨在实现减肥的强化生活方式干预对超重或肥胖的2型糖尿病成年患者心血管发病率和死亡率的10年影响。在这篇评论中，我们讨论了这项研究的结果及其临床意义。
