From the *Department of Nuclear Medicine and PET/CT Centre, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland; and †Institute of Pathology, Locarno, Switzerland.
Clin Nucl Med. 2014 Oct;39(10):e439-41. doi: 10.1097/RLU.0000000000000258.
We describe an unusual case of diffuse large B-cell lymphoma involving the vulva detected and staged by F-FDG PET/CT. An 83-year-old female patient with history of endometrial carcinoma underwent F-FDG PET/CT for follow-up. PET/CT detected an area of increased F-FDG uptake corresponding to a vulvar nodule; moderate and diffuse F-FDG uptake in the bone marrow was also evident. Based on these PET/CT findings, the patient underwent biopsy of the vulvar nodule. Histology demonstrated the presence of a diffuse large B-cell lymphoma of the vulva. Bone marrow biopsy was positive for lymphoid infiltration.
我们描述了一例由 F-FDG PET/CT 检测和分期的累及外阴的弥漫性大 B 细胞淋巴瘤的不寻常病例。一位 83 岁女性患者，有子宫内膜癌病史，行 F-FDG PET/CT 随访。PET/CT 检测到外阴结节处 F-FDG 摄取增加；骨髓也有中度和弥漫性 F-FDG 摄取。基于这些 PET/CT 发现，患者行外阴结节活检。组织学显示外阴弥漫性大 B 细胞淋巴瘤。骨髓活检呈淋巴细胞浸润阳性。
