From the *Department of Radiology, University of Washington Medical Center, Seattle; †Division of Gynecologic Oncology, Group Health Bellevue Medical Center, Bellevue, WA; and ‡Division of Nuclear Medicine & Clinical Molecular Imaging, Department of Radiology, Hospital of the University of Pennsylvania, University of Pennsylvania, Philadelphia, PA.
Clin Nucl Med. 2014 Jan;39(1):102-5. doi: 10.1097/RLU.0b013e3182a75cad.
A 38-year-old woman with metastatic malignant struma ovarii, including massive liver metastases and retroperitoneal lymphadenopathy, underwent ovarian resection and retroperitoneal lymph nodes excision, partial hepatectomy, and radiofrequency ablation for liver metastases. She underwent thyroidectomy and received three I treatments using recombinant human thyrotropin stimulation and radioiodine dosimetry. posttherapy I imaging, anatomic images, and thyroglobulin levels showed significant diminution in the tumor burdens and remarkable decline in thyroglobulin levels. This case provided valuable information on recombinant human thyrotropin-assisted I ablation in conjunction with dosimetry in an unusual presentation of iodine-avid malignant struma ovarii with bulky metastases.
一位 38 岁女性患有转移性恶性卵巢甲状腺肿，包括巨大的肝转移和腹膜后淋巴结病，接受了卵巢切除术和腹膜后淋巴结切除术、部分肝切除术和射频消融术治疗肝转移。她还进行了甲状腺切除术，并接受了三次 I 治疗，使用重组人促甲状腺激素刺激和放射性碘剂量测定。治疗后 I 影像学、解剖图像和甲状腺球蛋白水平显示肿瘤负荷明显减少，甲状腺球蛋白水平显著下降。该病例为碘敏感性恶性卵巢甲状腺肿伴巨大转移的罕见表现提供了关于重组人促甲状腺激素辅助 I 消融联合剂量测定的有价值信息。
