与移植物抗宿主病相关的银屑病样皮疹。

Psoriasiform eruption associated with graft-versus-host disease.

作者信息

Taguchi Shijima, Kawachi Yasuhiro, Fujisawa Yasuhiro, Nakamura Yasuhiro, Furuta Junichi, Otsuka Fujio

机构信息

Department of Dermatology, Faculty of Medicine, University of Tsukuba, 1-1-1, Tennodai, Tsukuba 305-8575, Japan.

出版信息

Cutis. 2013 Sep;92(3):151-3.

PMID:24153145

Abstract

Graft-versus-host disease (GVHD) is a frequent complication of bone marrow transplantation (BMT) that can be classified as acute or chronic. Characteristic cutaneous manifestations of acute GVHD, which generally occurs within 3 months following BMT, include maculopapular exanthema and perifollicular papular lesions. Psoriasiform skin eruption as a manifestation of acute GVHD is rare. We report the case of a 4-year-old boy who developed a generalized psoriasiform eruption shortly after undergoing an allogeneic BMT. Histologic features of both psoriasis and acute GVHD were present.

摘要

移植物抗宿主病（GVHD）是骨髓移植（BMT）常见的并发症，可分为急性或慢性。急性GVHD的典型皮肤表现通常发生在BMT后3个月内，包括斑丘疹和毛囊周围丘疹性病变。银屑病样皮疹作为急性GVHD的一种表现较为罕见。我们报告了一名4岁男孩在接受异基因BMT后不久出现全身性银屑病样皮疹的病例。该病例同时具有银屑病和急性GVHD的组织学特征。