Kami M, Kanda Y, Sasaki M, Takeda N, Tanaka Y, Saito T, Ogawa S, Honda H, Chiba S, Mitani K, Hirai H, Yazaki Y
Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.
Bone Marrow Transplant. 1998 Apr;21(7):721-3. doi: 10.1038/sj.bmt.1701159.
Chronic GVHD is one of the major complications of BMT, involving a variety of organs, but rarely involving the genitourinary system. We report a patient who simultaneously developed extensive chronic GVHD and phimosis after BMT. From the clinical course and pathological findings, chronic GVHD was considered to be responsible for the phimosis. Despite intensive immunosuppressive therapy, the phimosis persisted. Phimosis is a rare complication after BMT, which may often remain neglected. Possibility of this complication should be considered in patients with chronic GVHD.
慢性移植物抗宿主病是骨髓移植的主要并发症之一,可累及多个器官,但很少累及泌尿生殖系统。我们报告了1例骨髓移植后同时发生广泛慢性移植物抗宿主病和包茎的患者。从临床病程和病理结果来看,慢性移植物抗宿主病被认为是导致包茎的原因。尽管进行了强化免疫抑制治疗,包茎仍持续存在。包茎是骨髓移植后一种罕见的并发症,常易被忽视。对于慢性移植物抗宿主病患者,应考虑到这种并发症的可能性。