Lubart R, Lipovski A, Nitzan Y, Friedmann H
Departments of Chemistry and Physics, Bar-Ilan University, Ramat-Gan 52900, Israel.
Laser Ther. 2011;20(1):17-22. doi: 10.5978/islsm.20.17.
Visible light at high intensity was found to kill bacteria while low-power light in the visible and near infrared region enhances bacterial proliferation. The present review summarizes evidence demonstrating that the mechanism of visible light- bacteria interaction involves reactive oxygen species (ROS) generation. The ROS are photo induced by bacterial endogenous photosensitizers. Phototoxic effects were found to involve induction of high amounts of reactive oxygen species (ROS) by the bacteria while low amounts of ROS may promote their proliferation. Intense blue light, preferably at 415nm, is better than red light for bacteria killing.
高强度可见光可杀死细菌，而可见光和近红外区域的低功率光则会促进细菌增殖。本综述总结了相关证据，证明可见光与细菌相互作用的机制涉及活性氧（ROS）的产生。ROS由细菌内源性光敏剂光诱导产生。发现光毒性作用涉及细菌诱导产生大量活性氧，而少量的ROS可能会促进其增殖。高强度蓝光，最好是415nm的蓝光，在杀菌方面比红光更有效。
