Département de Chimie, Université de Sherbrooke , Sherbrooke, Quebec J1K 2R1, Canada.
J Am Chem Soc. 2013 Nov 6;135(44):16300-3. doi: 10.1021/ja408655n. Epub 2013 Oct 28.
Use of a given physiological stimulus to delicately deform polymer assemblies is a challenging topic. Here we develop synthetic block copolymers to construct a series of CO2-sensitive self-assembled nanostructures that can simulate controllable deformations of the organelles in different ways. By controlling the CO2 stimulation levels, one can modulate the size, shape, and morphology of the polymer aggregates, which is conducive to understanding the stimuli-triggered dynamic reshaping process of polymer assemblies in aqueous solution.
利用给定的生理刺激来精细地改变聚合物组装体是一个具有挑战性的课题。在这里，我们开发了合成嵌段共聚物，以构建一系列 CO2 敏感的自组装纳米结构，这些结构可以以不同的方式模拟细胞器的可控变形。通过控制 CO2 刺激水平，可以调节聚合物聚集体的大小、形状和形态，这有助于理解在水溶液中聚合物组装体受刺激触发的动态重塑过程。
