Zucchetto Antonella, Serraino Diego, Dal Maso Luigino, Birri Silvia, Francisci Silvia, Zigon Giulia, De Angelis Roberta
Tumori. 2013 May-Jun;99(3):318-26. doi: 10.1177/030089161309900306.
This analysis intended to estimate the incidence, mortality and prevalence time trends for the major cancer sites up to 2015 in the Friuli Venezia Giulia region, northeastern Italy, where a population-based cancer registry has been covering the whole area since 1995.
The MIAMOD method, a statistical back-calculation approach, was applied to estimate incidence, mortality and prevalence figures, in the period 1970-2015, using mortality data from the Italian National Institute of Statistics and relative survival data from Italian cancer registries.
We estimated that the cancer sites with the highest incidence rates in the forthcoming years will be breast in women (with an age-standardized incidence rate of 130 per 100,000 in 2015), prostate in men (97 per 100,000) and colon-rectum in both sexes (85 and 42 per 100,000 in men and women, respectively). The incidence rates for lung cancer will continue to decrease only in men (down to 43 per 100,000 in 2015). Although the decline in the mortality rates of lung, breast and colorectal cancers is likely to persist, these tumors will remain the big killers in the near future. The number of people living in Friuli Venezia Giulia after a cancer diagnosis is expected to continue to rise in particular for breast cancer (with a crude prevalence of 3,000 per 100,000 women in 2015), prostate cancer (1,700 per 100,000 men) and colorectal cancer (1,100 and 800 per 100,000 in men and women, respectively).
These estimates confirmed the epidemiological patterns in time trends of major cancer sites recorded in Friuli Venezia Giulia. They highlighted in particular the increasing number of people living after a cancer diagnosis as a result of population aging, earlier diagnosis and better prognosis, which warrants adequate public health policies.
本分析旨在估算意大利东北部弗留利-威尼斯朱利亚地区截至2015年主要癌症部位的发病率、死亡率及患病率的时间趋势,自1995年起该地区设有一个覆盖全区的基于人群的癌症登记处。
采用MIAMOD方法,一种统计反向推算方法,利用意大利国家统计局的死亡率数据和意大利癌症登记处的相对生存数据,估算1970 - 2015年期间的发病率、死亡率及患病率数据。
我们估计,未来几年发病率最高的癌症部位将是女性乳腺癌(2015年年龄标准化发病率为每10万人130例)、男性前列腺癌(每10万人97例)以及男女两性的结肠直肠癌(男性和女性分别为每10万人85例和42例)。肺癌发病率仅在男性中继续下降(2015年降至每10万人43例)。尽管肺癌、乳腺癌和结肠直肠癌的死亡率下降趋势可能持续,但这些肿瘤在不久的将来仍将是主要杀手。弗留利-威尼斯朱利亚地区癌症诊断后存活的人数预计将继续上升,尤其是乳腺癌(2015年每10万女性粗患病率为3000例)、前列腺癌(每10万男性1700例)和结肠直肠癌(男性和女性分别为每10万人1100例和800例)。
这些估计结果证实了弗留利-威尼斯朱利亚地区主要癌症部位时间趋势的流行病学模式。它们特别强调了由于人口老龄化、早期诊断和更好的预后,癌症诊断后存活人数的增加,这需要制定适当的公共卫生政策。