特伦蒂诺-上阿迪杰地区癌症负担的估计。

Estimates of cancer burden in Trentino-Alto Adige.

作者信息

Piffer Silvano, Gentilini Maria, Rizzello Roberto, Mazzoleni Guido, Bellù Francesco, Rossi Silvia

出版信息

Tumori. 2013 May-Jun;99(3):296-307. doi: 10.1177/030089161309900304.

DOI:10.1177/030089161309900304

PMID:24158058

Abstract

AIMS AND BACKGROUND

The Trentino-Alto Adige region is composed of two autonomous provinces (Trento and Bolzano), each with its own cancer registry. The registries' total coverage is 100% of the regional population. The main difference between the two provinces in terms of cancer epidemiology is related to the prostate cancer incidence and survival, with higher values in Bolzano. This paper provides an update until 2015 of the basic epidemiological indicators for seven major cancers for the entire region.

METHODS

The indicators were estimated by means of the MIAMOD method, a statistical back-calculation approach to derive incidence and prevalence figures starting from mortality and relative survival data. Mortality data were provided by ISTAT for the period 1970-2002 while survival was modeled on the basis of published data from the Italian cancer registries.

RESULTS

The estimates for 2012 show that breast cancer was the most common cancer in women and prostate cancer was most common in men. Incidence and mortality were decreasing for cervix cancer and stomach cancer in both genders during the whole study period. The lung cancer incidence and mortality were decreasing in men but increasing in women. The colorectal cancer incidence rose in both genders while the mortality was decreasing in women. The incidence of skin melanoma increased in both sexes, while the mortality remained very low. The breast cancer incidence was increasing up to 2015 while the mortality was declining since 1986. The prostate cancer incidence increased up to 2006, thereafter the rates stabilized while mortality started to decrease in the early 2000s. The highest mortality rates were estimated for lung cancer in men and breast cancer in women.

CONCLUSIONS

Lifestyle plays an important role in cancer trends, as does organized screening for early detection of cervix, breast and colorectal cancer. The provincial data on risk factor distribution and adherence to and coverage of organized screening are satisfactory and their optimization may allow additional benefits in terms of public health.

摘要

目的与背景

特伦蒂诺-上阿迪杰地区由两个自治省（特伦托和博尔扎诺）组成，每个省都有自己的癌症登记处。这些登记处的总覆盖范围为该地区全部人口。两省在癌症流行病学方面的主要差异与前列腺癌的发病率和生存率有关，博尔扎诺的相关数值更高。本文提供了该地区直至2015年的七种主要癌症基本流行病学指标的最新情况。

方法

这些指标通过MIAMOD方法进行估算，MIAMOD是一种从死亡率和相对生存数据推导发病率和患病率数据的统计反向计算方法。1970 - 2002年期间的死亡率数据由意大利国家统计局提供，而生存率则根据意大利癌症登记处公布的数据进行建模。

结果

2012年的估算结果表明，乳腺癌是女性中最常见的癌症，前列腺癌是男性中最常见的癌症。在整个研究期间，宫颈癌和胃癌在男女两性中的发病率和死亡率均呈下降趋势。男性肺癌的发病率和死亡率在下降，而女性则在上升。男女两性的结直肠癌发病率均有所上升，而女性的死亡率在下降。皮肤黑色素瘤的发病率在两性中均有所增加，但其死亡率仍然很低。乳腺癌的发病率在2015年前一直在上升，而自1986年以来死亡率一直在下降。前列腺癌的发病率在2006年前上升，此后趋于稳定，而死亡率在21世纪初开始下降。估计男性肺癌和女性乳腺癌的死亡率最高。