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胆总管十二指肠吻合术作为良性和恶性胆总管远端狭窄的首选胆肠旁路术。

Choledochoduodenostomy as the biliary-enteric bypass of choice for benign and malignant distal common bile duct strictures.

作者信息

Luu Carrie, Lee Byrne, Stabile Bruce E

机构信息

Department of Surgery, Harbor-UCLA Medical Center, Torrance, California, USA.

出版信息

Am Surg. 2013 Oct;79(10):1054-7.

PMID:24160798
Abstract

Choledochoduodenostomy (including hepaticoduodenostomy) for common bile duct (CBD) strictures has been underused because of concerns regarding postoperative duodenal fistula and cholangitis attending the so-called "sump syndrome." An institutional retrospective review of 55 consecutive choledochoduodenostomy procedures for CBD strictures from 1995 to 2011 was performed to examine its suitability as the biliary-enteric bypass procedure of choice. There were 30 male (55%) and 25 female (45%) patients with a mean age of 49 years (range, 13 to 73 years). Thirty-seven (67%) patients had benign CBD strictures and 18 (33%) had unresectable periampullary adenocarcinomas. Forty-nine (89%) underwent choledochoduodenostomy and six (11%) underwent hepaticoduodenostomy. There were no 30-day postoperative deaths, anastomotic leaks, or intra-abdominal abscesses. Five patients (9%) sustained Clavien Grade III or IV complications. Over a mean long-term follow-up of 29 months (range, 1 to 162 months), there was one anastomotic stricture successfully managed by endoscopic dilation and temporary stenting. Liver function tests in all other patients returned to and remained within normal limits. We conclude that choledochoduodenostomy is the preferred biliary-enteric bypass for both benign and malignant distal CBD strictures because of its ease, safety, and durability. Persistent fears of duodenal fistula and the "sump syndrome" are not warranted by the empiric data and should be abandoned.

摘要

由于担心术后十二指肠瘘和所谓“贮袋综合征”相关的胆管炎,胆总管(CBD)狭窄的胆总管十二指肠吻合术(包括肝十二指肠吻合术)一直未得到充分应用。对1995年至2011年间连续进行的55例胆总管十二指肠吻合术治疗CBD狭窄的病例进行了机构回顾性研究,以检验其作为首选胆肠旁路手术的适用性。共有30例男性(55%)和25例女性(45%)患者,平均年龄49岁(范围13至73岁)。37例(67%)患者为良性CBD狭窄,18例(33%)为不可切除的壶腹周围腺癌。49例(89%)接受了胆总管十二指肠吻合术,6例(11%)接受了肝十二指肠吻合术。术后30天内无死亡、吻合口漏或腹腔内脓肿发生。5例患者(9%)出现Clavien III级或IV级并发症。平均长期随访29个月(范围1至162个月),有1例吻合口狭窄通过内镜扩张和临时支架置入成功处理。所有其他患者的肝功能检查恢复并维持在正常范围内。我们得出结论,由于胆总管十二指肠吻合术操作简便、安全且持久,它是良性和恶性远端CBD狭窄首选的胆肠旁路手术。基于经验数据,对十二指肠瘘和“贮袋综合征”的持续担忧是没有根据的,应该摒弃。

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