Kutzner J, Klose K, Keller E
Strahlentherapie. 1985 Nov;161(11):669-72.
Carcinoma of the common hepatic bile duct or common bile duct were treated by interstitial irradiation with gold seeds using the percutaneous transhepatic drainage partly boosted by external irradiation. The interstitial dose of 50 Gy was given in two applications and 40 Gy by linac. Twice histological examination showed wide tumor destruction of local irradiation, but also much more tumor extension than seen before by diagnostic investigation. Mostly the therapy is only palliative because of the infiltration of liver and lymph nodes.
肝总管或胆总管癌采用金籽源组织间照射治疗，经皮经肝引流辅助，部分联合外照射。组织间照射分两次给予50 Gy剂量，直线加速器给予40 Gy剂量。两次组织学检查显示局部照射造成肿瘤广泛破坏，但肿瘤浸润范围比诊断性检查所见的更广。由于肿瘤侵犯肝脏和淋巴结，多数情况下该治疗仅为姑息性治疗。
