Lien H H, Brodahl U, Telhaug R, Holthe H, Fosså S D
Acta Radiol Diagn (Stockh). 1985 Sep-Oct;26(5):507-10. doi: 10.1177/028418518502600502.
Computed tomography was performed before and after CVB therapy (cis-platinum, vinblastine, bleomycin) in 42 patients with metastatic testicular carcinoma. Twenty-one of these (3 symptomatic, 18 asymptomatic) developed subpleural pulmonary abnormalities which were streaky or reticular in 7, homogeneous with a broad base against pleura in 3 and had a mixed pattern in 11 patients. Histologic examination was obtained in 3 patients and showed fibrosis with no tumor tissue. Twelve patients with marked CVB induced abnormalities underwent repeat CT within 6 to 24 weeks. Changes disappeared spontaneously in 7, diminished in 3 and increased in 2 of these. Further conventional chest radiography of the latter two revealed complete regression of changes. Pulmonary lesions induced by CVB therapy should be kept in mind at follow-up so that an erroneous diagnosis of tumor progression is not made.
对42例转移性睾丸癌患者在进行顺铂、长春碱、博来霉素（CVB）治疗前后均进行了计算机断层扫描。其中21例（3例有症状，18例无症状）出现胸膜下肺部异常，7例为条纹状或网状，3例为与胸膜广泛基底相连的均匀性病变，11例为混合性病变。3例患者进行了组织学检查，显示为纤维化，无肿瘤组织。12例CVB引起明显异常的患者在6至24周内进行了重复CT检查。其中7例异常自发消失，3例减轻，2例加重。对后2例患者进一步的传统胸部X线检查显示病变完全消退。在随访时应牢记CVB治疗引起的肺部病变，以免误诊为肿瘤进展。
