Culley Celia L, Ramsey Tasha D, Mugyenyi Godfrey, Kiwanuka Gertrude N, Ngonzi Joseph, Macleod Stuart, Koren Gideon, Grunau Brian E, Wiens Matthew O
J Popul Ther Clin Pharmacol. 2013;20(3):e321-33. Epub 2013 Oct 18.
The prevalence of general alcohol use in many countries of sub-Saharan Africa (SSA) is high. However, research examining alcohol use in among pregnant women within this population is limited. A review of the current status of research examining the prevalence of alcohol exposed pregnancies (AEP) is required to inform future research aiming to decrease this occurrence and its subsequent socio-economic complications.
The primary objective was to identify all published papers estimating prevalence and risk-factors of alcohol use among pregnant women in SSA. A secondary objective was to determine changes in alcohol use following pregnancy recognition.
PubMed/Medline, Embase, IPA, CINAHL were systematically searched using MeSH terms and keywords from inception date to March 2013. Studies from SSA reporting prevalence of alcohol use among pregnant women were included.
Twelve studies were identified. Studies varied significantly according to design and study population. Prevalence of alcohol use during pregnancy ranged from 2.2%-87%. The most important risk-factors for alcohol use included tobacco use, partner violence, urban living, and having a male partner who drank alcohol. Only three studies examined changes in alcohol use prior to and following pregnancy recognition with absolute reductions of between 9% and 15%.
Although the burden of alcohol use during pregnancy is likely a significant problem, limited data currently exist for the majority of SSA countries. Furthermore, significant variation likely exists within various populations. Further research is required to explore alcohol use in pregnancy. Strategies to decrease AEP must be developed and implemented in standard pre-natal care.
撒哈拉以南非洲(SSA)许多国家的一般酒精使用流行率很高。然而,对该人群中孕妇酒精使用情况的研究有限。需要对酒精暴露妊娠(AEP)流行率的研究现状进行综述,以为未来旨在减少这种情况及其后续社会经济并发症的研究提供信息。
主要目的是识别所有已发表的估计SSA孕妇酒精使用流行率和风险因素的论文。次要目的是确定妊娠确认后酒精使用的变化。
从创刊日期到2013年3月,使用医学主题词和关键词对PubMed/Medline、Embase、IPA、CINAHL进行系统检索。纳入报告SSA孕妇酒精使用流行率的研究。
共识别出12项研究。根据设计和研究人群,研究差异很大。孕期酒精使用流行率在2.2%至87%之间。酒精使用的最重要风险因素包括吸烟、伴侣暴力、城市生活以及有饮酒的男性伴侣。只有三项研究考察了妊娠确认前后酒精使用的变化,绝对减少率在9%至15%之间。
尽管孕期酒精使用负担可能是一个重大问题,但目前大多数SSA国家的数据有限。此外,不同人群中可能存在显著差异。需要进一步研究孕期酒精使用情况。必须在标准产前护理中制定并实施减少AEP的策略。