Response of a neuronal membrane to applied sinusoidal currents.

The membrane model of Connor and Stevens was used to calculate the response of a neuron to an injected sinusoidal current. This stimulating current simulates the effects of cell exposure to incident time-harmonic electromagnetic fields. The theoretical results obtained with this model were compared with intracellular recordings carried out during the injection of a sinusoidal transmembrane current through a single microelectrode. Experimental and theoretical data were substantially in agreement for current amplitudes that can be induced by actual exposure conditions.