多巴胺对棕色脂肪脂肪细胞氧化代谢的影响。
The effect of dopamine upon oxidative metabolism of brown fat adipocytes.
作者信息
Maxwell G, Crompton S, Smyth C
出版信息
Eur J Pharmacol. 1985 Oct 22;116(3):293-7. doi: 10.1016/0014-2999(85)90165-7.
PMID:2416573
Abstract
The effect of dopamine upon the oxygen consumption (QO2) of brown fat adipocytes was measured by polarography. The results showed a marked stimulation of QO2 by dopamine, similar to that induced by noradrenaline. The dopamine response could be blocked by haloperidol, butaclamol, propranolol and by high concentrations of tolazoline. These results suggest a role for dopamine in energy release from brown fat.
摘要
通过极谱法测定了多巴胺对棕色脂肪脂肪细胞耗氧量（QO2）的影响。结果显示，多巴胺对QO2有显著刺激作用，类似于去甲肾上腺素所诱导的作用。多巴胺反应可被氟哌啶醇、布他拉莫、普萘洛尔以及高浓度的妥拉唑啉阻断。这些结果表明多巴胺在棕色脂肪的能量释放中起作用。
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