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Evidence for possible increase of sodium channel open time and involvement of Na/Ca exchange by a new positive inotropic drug: OPC-8212.

作者信息

Lathrop D A, Schwartz A

出版信息

Eur J Pharmacol. 1985 Nov 19;117(3):391-2. doi: 10.1016/0014-2999(85)90016-0.

DOI:10.1016/0014-2999(85)90016-0
PMID:2416581
Abstract
摘要

相似文献

1
Evidence for possible increase of sodium channel open time and involvement of Na/Ca exchange by a new positive inotropic drug: OPC-8212.一种新型正性肌力药物OPC-8212可能增加钠通道开放时间及涉及钠/钙交换的证据
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Studies on the mechanism of action of 3, 4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)-qu inolinone (OPC-8212), a new positive inotropic drug. Enzyme activities and Ca2+ transport processes of sarcolemma and intracellular organelles.新型正性肌力药物3,4-二氢-6-[4-(3,4-二甲氧基苯甲酰基)-1-哌嗪基]-2(1H)-喹啉酮(OPC-8212)的作用机制研究。肌膜和细胞内细胞器的酶活性及Ca2+转运过程。
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J Physiol. 1988 May;399:537-58. doi: 10.1113/jphysiol.1988.sp017095.

引用本文的文献

1
OPC-8212 in the treatment of congestive heart failure: results of a pilot study.OPC-8212治疗充血性心力衰竭：一项初步研究的结果
Cardiovasc Drugs Ther. 1988 Dec;2(5):653-60. doi: 10.1007/BF00054205.
2
Cyclic AMP-dependent and cyclic AMP-independent actions of a novel cardiotonic agent, OPC-8212.新型强心剂OPC-8212的环磷酸腺苷依赖性和非环磷酸腺苷依赖性作用
Naunyn Schmiedebergs Arch Pharmacol. 1988 Dec;338(6):692-8. doi: 10.1007/BF00165636.
3
Selective updates on mechanisms of action of positive inotropic agents.正性肌力药物作用机制的选择性更新。
Mol Cell Biochem. 1987 Aug;76(2):97-112. doi: 10.1007/BF00223475.
4
Phosphodiesterase inhibition by new cardiotonic agents: mechanism of action and possible clinical relevance in the therapy of congestive heart failure.新型强心剂对磷酸二酯酶的抑制作用：作用机制及其在充血性心力衰竭治疗中可能的临床意义
Klin Wochenschr. 1989 Jun 15;67(12):605-15. doi: 10.1007/BF01718141.
5
Effects of a new 1,3-thiazole derivative ZSY-39 on force of contraction and cyclic AMP content in canine ventricular muscle.
Cardiovasc Drugs Ther. 1990 Aug;4(4):1127-34. doi: 10.1007/BF01856509.
6
Effect of OPC-8490 on the membrane potentials and membrane currents of single guinea-pig myocytes.
Cardiovasc Drugs Ther. 1990 Jun;4(3):713-7. doi: 10.1007/BF01856559.
7
Subcellular mechanism of the positive inotropic effect of a new quinolinone derivative OPC-8490 on the dog ventricular myocardium.
Heart Vessels. 1991;6(3):158-67. doi: 10.1007/BF02058281.