Mustafa S, Zofair S M
Int J Environ Anal Chem. 1985;22(1-2):155-9. doi: 10.1080/03067318508076417.
Exposure of Puntius stigma to sublethal dose of DDT (0.05 ppm) for 15 days decreased the liver concentrations of protein and DNA from 65 +/- 0.91 to 63 +/- 0.78 mg/100 mg and 669 +/- 17 to 575 +/- 14 micrograms/100 mg, respectively whereas RNA increased from 8214 +/- 318 to 8929 +/- 209 micrograms/100 mg. Biotransformation products of this hydrocarbon interfered in the pathways of protein biosynthesis and induced proteolysis in hepatic tissues. The resulting changes were explained in the light of hypertrophication of liver parenchyma and inter-relationships of chemical constituents.
将斑蒂尾鲃暴露于亚致死剂量的滴滴涕（0.05 ppm）中15天，其肝脏中的蛋白质浓度从65±0.91毫克/100毫克降至63±0.78毫克/100毫克，DNA浓度从669±17微克/100毫克降至575±14微克/100毫克，而RNA浓度则从8214±318微克/100毫克增加至8929±209微克/100毫克。这种碳氢化合物的生物转化产物干扰了蛋白质生物合成途径，并在肝组织中诱导了蛋白水解。根据肝实质的肥大以及化学成分之间的相互关系对所产生的变化进行了解释。
