氯氮平治疗边缘型人格障碍个体的自伤行为。
Clozapine for self-injurious behavior in individuals with borderline personality disorder.
机构信息
Central Regional Hospital, 300 Veazey Road, Butner, NC 27509, USA.
出版信息
Ther Adv Psychopharmacol. 2013 Oct;3(5):272-4. doi: 10.1177/2045125313484323.
Abstract
Prior reports suggest that clozapine can markedly reduce aggression and self-injurious behavior in patients with borderline personality disorder (BPD). We present a series of four patients with BPD and persistent self-injurious behavior treated with clozapine at a state psychiatric hospital. After treatment with clozapine these patients ceased self-injurious behaviors and aggression, and no longer required intensive levels of observation or restrictive procedures. All were successfully discharged from the hospital soon after initiation of clozapine. Clozapine appears to be efficacious in the management of chronic suicidality, self-injurious behaviors and aggression in patients with severe BPD.
摘要
先前的报告表明，氯氮平可以显著减少边缘型人格障碍（BPD）患者的攻击行为和自残行为。我们在一家州立精神病院介绍了一系列 4 名接受氯氮平治疗的 BPD 患者，这些患者持续存在自残行为。氯氮平治疗后，这些患者停止了自残行为和攻击行为，不再需要密集的观察或限制程序。所有患者在开始氯氮平治疗后不久都成功出院。氯氮平似乎对严重 BPD 患者的慢性自杀意念、自残行为和攻击行为的治疗有效。
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