慢性肾脏病与急性缺血性卒中患者的反复缺血相关，但与出血性转化无关。
CKD is associated with recurrent ischemia but not with hemorrhagic transformation in acute ischemic stroke patients.
作者信息
Micozkadioglu Hasan, Ozelsancak Ruya, Giray Semih, Arlier Zulfikar
机构信息
Department of Nephrology , and.
出版信息
Ren Fail. 2014 Mar;36(2):217-21. doi: 10.3109/0886022X.2013.846794. Epub 2013 Oct 29.
BACKGROUND
We investigated the associations of Recurrent Ischemic Stroke (RIS) and Hemorrhagic Transformation (HT) with CKD in acute ischemic stroke patients.
METHOD
The subjects were 160 patients, divided into two groups: with eGFR <60 mL/min/1.73 m2 (CKD), with eGFR ≥60 mL/min/1.73 m2 (without CKD).
RESULTS
Subjects having DM (p = 0.018), CKD (p = 0.025) and treated with ACEI/ARB (p = 0.039) revealed association with RIS. Regression analysis disclosed only CKD (p = 0.04). Carotid artery stenosis (p = 0.030) and serum calcium levels (p = 0.013) showed significant association with HT.
CONCLUSION
Our results disclosed that CKD could be a risk factor for RIS. There is no relation between CKD and HT.
背景
我们研究了急性缺血性脑卒中患者复发性缺血性卒中（RIS）和出血性转化（HT）与慢性肾脏病（CKD）之间的关联。
方法
研究对象为160例患者，分为两组：估算肾小球滤过率（eGFR）<60 mL/min/1.73 m²（CKD组），eGFR≥60 mL/min/1.73 m²（非CKD组）。
结果
患有糖尿病（p = 0.018）、CKD（p = 0.025）且接受血管紧张素转换酶抑制剂/血管紧张素Ⅱ受体阻滞剂（ACEI/ARB）治疗（p = 0.039）的患者显示与RIS有关联。回归分析仅显示CKD（p = 0.04）与RIS有关。颈动脉狭窄（p = 0.030）和血清钙水平（p = 0.013）与HT显示出显著关联。
结论
我们的结果表明，CKD可能是RIS的一个危险因素。CKD与HT之间无关联。
Zotero 插件