Giese Jeannie K
The Allergy & Asthma Center, Fort Wayne, Indiana.
J Am Assoc Nurse Pract. 2014 Feb;26(2):102-109. doi: 10.1111/1745-7599.12029. Epub 2013 Apr 29.
To explore if being overweight or obese influenced asthma control in pediatric patients ages 7-18 years with persistent asthma seen in an asthma specialty office.
A retrospective chart analysis of children with an asthma diagnosis seen within an asthma specialty practice from December 1, 2009 to May 31, 2010 was utilized. Normal weight, overweight, and obese children were compared. The following four variables were examined: the number of controller asthma medications prescribed; the number of systemic corticosteroids prescribed in 1 year for asthma exacerbations; FEV1 % of predicted; and FEV1 /FVC% of predicted.
No statistically significant difference was found between the three weight groups for the number of controller medications prescribed, number of systemic corticosteroids in 1 year, or FEV1 /FVC. A statistically significant difference was found for FEV1 %, F (2,430) = 5.51, p = .004. Overweight children had the highest mean FEV1 %, 92.47 ± 16.74%. A statistically significant difference was found between the normal weight and overweight groups, p = .0104 and the overweight and obese groups, p = .0233.
In clinical practice, obese children often report more asthma symptoms. This inquiry did not show an objective decline in asthma control associated with overweight or obesity.
探讨超重或肥胖是否会影响在哮喘专科门诊就诊的7至18岁持续性哮喘儿科患者的哮喘控制情况。
对2009年12月1日至2010年5月31日在哮喘专科诊所确诊为哮喘的儿童进行回顾性病历分析。对体重正常、超重和肥胖的儿童进行比较。检查了以下四个变量:开具的哮喘控制药物数量;1年内因哮喘发作开具的全身用糖皮质激素数量;预测的第一秒用力呼气容积(FEV1)百分比;以及预测的FEV1/用力肺活量(FVC)百分比。
在开具的控制药物数量、1年内全身用糖皮质激素数量或FEV1/FVC方面,三个体重组之间未发现统计学上的显著差异。在FEV1百分比方面发现了统计学上的显著差异,F(2,430)=5.51,p = 0.004。超重儿童的平均FEV1百分比最高,为92.47±16.74%。在正常体重组和超重组之间发现了统计学上的显著差异,p = 0.0104,在超重组和肥胖组之间发现了统计学上的显著差异,p = 0.0233。
在临床实践中,肥胖儿童常报告更多哮喘症状。本研究未显示与超重或肥胖相关的哮喘控制客观下降情况。