Clinique Médicale, Hôpital universitaire St. Pierre, University of Brussels, Belgium.
Diabetologia. 1966 Apr;1(3-4):155-61. doi: 10.1007/BF01257906.
Twenty patients, selected on the basis of simultaneous existence of overt diabetes and marked hirsutism, were submitted to clinical and biological investigations. Obesity, hypertension and angiopathy were present in most of these patients. Metabolic investigations afforded valuable proof of hypercorticism associated with depressed activity of insulin. Nevertheless, increased steroiduria was also observed in groups of non-hirsute diabetic women carefully paired for age. Thus the Achard-Thiers syndrome cannot be separated with certainty from common overt diabetes.
二十名患者,根据明显的糖尿病和明显多毛症同时存在的基础上被选择,进行了临床和生物学研究。这些患者大多数都有肥胖、高血压和血管疾病。代谢研究提供了皮质醇过多与胰岛素活性降低相关的有价值的证据。然而,在年龄相匹配的非多毛症糖尿病女性组中也观察到了类固醇尿增多。因此,阿查尔德-蒂尔斯综合征不能与普通显性糖尿病明确区分。