Cosmetic Ingredient Review, 1101 17th Street, NW, Suite 412, Washington, DC 20036, USA. Email:
Int J Toxicol. 2013 Sep-Oct;32(5 Suppl):65S-72S. doi: 10.1177/1091581813507089.
The Cosmetic Ingredient Review Expert Panel (Panel) reviewed the safety of calcium sodium borosilicate, calcium aluminum borosilicate, calcium titanium borosilicate, silver borosilicate, and zinc borosilicate as used in cosmetics. These borosilicate glasses function mostly as bulking agents. Available animal and human data were considered along with data from a previous safety assessment of magnesium silicates. The similar structure, properties, functions, and uses of these ingredients enabled grouping them and using the available toxicological data to assess the safety of the entire group. Data submitted on calcium borosilicate, which is not a cosmetic ingredient, are also included as additional support for the safety of borosilicate glass ingredients. The Panel concluded that borosilicate glasses are safe as cosmetic ingredients in the practices of use and concentration as given in this safety assessment.
化妆品成分评估专家小组(小组)审查了钙钠硼硅酸盐、钙铝硼硅酸盐、钙钛硼硅酸盐、银硼硅酸盐和锌硼硅酸盐在化妆品中的安全性。这些硼硅酸盐玻璃主要用作增稠剂。评估时考虑了现有的动物和人体数据,以及之前对硅酸镁安全性的评估数据。由于这些成分具有相似的结构、性质、功能和用途,因此可以将它们分组,并使用现有的毒理学数据来评估整个组的安全性。关于钙硼硅酸盐的数据也包括在内,因为它不是化妆品成分,这为硼硅酸盐玻璃成分的安全性提供了额外的支持。小组得出结论,硼硅酸盐玻璃在本安全性评估中给出的使用和浓度实践中是安全的化妆品成分。