Aumüller G, Schmitt J, Enderle U, Seitz J
Anat Anz. 1985;160(2):123-31.
The distribution of tissue- and organ specific marker proteins has been studied in the accessory sex glands of different mammals. Tissue specific marker proteins are desmin, actin, vimentin, laminin, keratin and related proteins which are well suited to identify smooth muscle cells, fibrocytes, basal cells of the epithelium etc. Secretory proteins were used as markers for organ specificity, e.g. secretory acid phosphatase, prostate specific antigen. In the accessory sex glands of the rat a most complicated pattern of typical secretions was identified using specific antibodies. As deduced from this pattern functional relations are likely between the lateral prostate and the seminal vesicle and the dorsal prostate and the coagulation gland respectively. The ventral prostate of the rat has a particular range among these glands and is homologous to the human prostate.
已对不同哺乳动物附属性腺中组织和器官特异性标记蛋白的分布进行了研究。组织特异性标记蛋白有结蛋白、肌动蛋白、波形蛋白、层粘连蛋白、角蛋白及相关蛋白，它们非常适合用于识别平滑肌细胞、纤维细胞、上皮基底细胞等。分泌蛋白被用作器官特异性的标记物，例如分泌性酸性磷酸酶、前列腺特异性抗原。利用特异性抗体在大鼠附属性腺中鉴定出了一种极其复杂的典型分泌物模式。根据这种模式推断，侧叶前列腺与精囊之间以及背叶前列腺与凝固腺之间可能分别存在功能关系。大鼠的腹侧前列腺在这些腺体中具有独特地位，并且与人类前列腺同源。
