Weng J T, Smith D E, Moulder P V
Ann Thorac Surg. 1986 Jan;41(1):106-12. doi: 10.1016/s0003-4975(10)64510-9.
Cardiac arrhythmias arise from abnormalities of impulse initiation or impulse conduction or both. A review of the electrophysiological mechanisms of the genesis of cardiac arrhythmias and of the electrophysiological principles of the treatment of the cardiac arrhythmias leads to: categorization of antiarrhythmic drugs into five classes based on their dominant cardiac electrophysiological actions; a series of categories of their effects on impulse initiation and impulse conduction in different types of cardiac cells; and a systematic approach to pharmacological management of cardiac arrhythmias.
心律失常源于冲动起始异常或冲动传导异常，或两者皆有。回顾心律失常发生的电生理机制以及心律失常治疗的电生理原则，可得出以下结果：抗心律失常药物根据其主要的心脏电生理作用分为五类；一系列关于它们对不同类型心肌细胞冲动起始和冲动传导影响的类别；以及心律失常药物治疗的系统方法。
