纤毛虫游仆虫细胞周期中电压依赖性钙电流的变化

Changes in voltage-dependent calcium currents during the cell cycle of the ciliate Stylonychia.

作者信息

Deitmer J W, Ivens I, Pernberg J

出版信息

Exp Cell Res. 1986 Feb;162(2):549-54. doi: 10.1016/0014-4827(86)90359-9.

Abstract

Electrophysiological properties of the hypotrichous ciliate Stylonychia mytilus were studied at two stages of its cell cycle: within 30 min after cell division and several hours thereafter. The action potential wave form, and the relative amount of two voltage-dependent calcium inward currents are significantly different in 'young' daughter cells as compared with 'adult' cells. The ratio between total inward and outward current is also larger in 'young' cells. The results provide evidence that during its cell cycle Stylonychia undergoes qualitative developmental changes with respect to its ionic channels in the membrane. These changes may explain the different cell behaviour observed up to 1 h after cell division.

摘要

在纤毛虫类的稀毛草履虫（Stylonychia mytilus）细胞周期的两个阶段对其电生理特性进行了研究：细胞分裂后30分钟内以及此后数小时。与“成年”细胞相比，“年轻”子细胞的动作电位波形以及两种电压依赖性钙内向电流的相对量存在显著差异。“年轻”细胞中总内向电流与外向电流的比率也更大。结果表明，在细胞周期中，稀毛草履虫在膜离子通道方面经历了质的发育变化。这些变化可能解释了在细胞分裂后长达1小时内观察到的不同细胞行为。