Grönblad M, Korkala O, Liesi P, Karaharju E
Acta Orthop Scand. 1985 Dec;56(6):484-6. doi: 10.3109/17453678508993040.
Substance P-immunofluorescent nerves, which are closely connected to pain transmission, were shown in human knee synovial membrane and menisci. Both tissues also contained enkephalin-immunofluorescent nerves, which are probably involved in the modulation of pain transmission. Previous suggestions on the presence of nociceptive receptors in these non-cartilaginous joint structures, made on a histological basis, are thus confirmed by a specific immunohistochemical method.
P物质免疫荧光神经与疼痛传递密切相关,在人膝关节滑膜和半月板中被发现。这两种组织中还含有脑啡肽免疫荧光神经,它们可能参与疼痛传递的调节。因此,先前基于组织学对这些非软骨关节结构中伤害性感受器存在的推测,通过一种特定的免疫组织化学方法得到了证实。