Narayan T M, Ludwig C, Sato S
Electroencephalogr Clin Neurophysiol. 1986 Mar;63(3):239-41. doi: 10.1016/0013-4694(86)90091-x.
A wide variety of anatomical sites have been implicated in the pathogenesis of torticollis, based primarily on animal studies. These include lesions in the mesencephalic tegmentum, third ventricle, diencephalon, pre-tectal area, prestitial nucleus of the mid-brain, cervical cord, atlanto-axial junction and motor cortex, amongst others. This study describes the use of multimodality evoked potentials including visual, auditory, bilateral median and peroneal somatosensory evoked responses, undertaken in patients with idiopathic spasmodic torticollis. An attempt was made to non-invasively identify any physiological disruption along these major pathways which could help locate a causative lesion. Normal evoked responses were obtained both ipsilateral and contralateral to the affected side in all patients. It is concluded that the lesion in idiopathic spasmodic torticollis does not discernibly involve the visual, auditory or motor somatosensory pathways.
主要基于动物研究,多种解剖部位被认为与斜颈的发病机制有关。这些部位包括中脑被盖、第三脑室、间脑、顶盖前区、中脑间质核、颈髓、寰枢关节和运动皮层等。本研究描述了对特发性痉挛性斜颈患者进行的多模态诱发电位检测,包括视觉、听觉、双侧正中神经和腓总神经体感诱发电位。试图通过非侵入性方法确定这些主要通路中是否存在任何生理功能紊乱,以帮助定位致病病变。所有患者患侧的同侧和对侧均获得了正常的诱发电位反应。得出的结论是,特发性痉挛性斜颈的病变并未明显累及视觉、听觉或运动体感通路。