Beijing National Laboratory of Molecular Science, Key Laboratory of Green Printing, Institute of Chemistry, Chinese Academy of Sciences, Beijing (PR China), Fax: (+86) 10-62559373; University of Chinese Academy of Sciences, Yuquan Road #19, Shijingshan, 10049, Beijing (PR China).
ChemSusChem. 2014 Jan;7(1):202-9. doi: 10.1002/cssc.201300542. Epub 2013 Nov 5.
Levulinic acid is an important platform molecule from biomass-based renewable resources. A sustainable manufacturing process for this chemical and its derivatives is the enabling factor to harness the renewable resource. An integrated catalytic process to directly convert furfural to levulinate ester was developed based on a bifunctional catalyst of Pt nanoparticles supported on a ZrNb binary phosphate solid acid. The hydrogenation of furfural and the following alcoholysis of furfuryl alcohol were performed over this catalyst in a one-pot conversion model. Mesoporous ZrNb binary phosphate was synthesized by a sol-gel method and had a high surface area of 170.1 m(2) g(-1) and a large average pore size of around 8.0 nm. Pt nanoparticles remained in a monodisperse state on the support, and the reaction over Pt/ZrNbPO4 (Pt loading: 2.0 wt%; Zr/Nb, 1:1) gave a very high selectivity to levulinate derivatives (91% in total). The sustainability of this conversion was greatly improved by the process intensification based on the new catalyst, mild reaction conditions, cost abatement in separation and purification, and utilization of green reagents and solvents.
乙酰丙酸是一种重要的平台分子，来源于基于生物质的可再生资源。可持续的这种化学品及其衍生物的制造工艺是利用可再生资源的关键因素。基于 Pt 纳米粒子负载在 ZrNb 二元磷酸盐固体酸上的双功能催化剂，开发了一种将糠醛直接转化为乙酰丙酸酯的集成催化工艺。在一锅转化模型中，该催化剂同时进行糠醛的加氢和糠醇的随后醇解。采用溶胶-凝胶法合成了介孔 ZrNb 二元磷酸盐，其比表面积高达 170.1 m(2) g(-1)，平均孔径约为 8.0 nm。Pt 纳米粒子均匀地负载在载体上，Pt/ZrNbPO4（Pt 负载量：2.0wt%；Zr/Nb，1:1）上的反应表现出很高的乙酰丙酸衍生物选择性（总收率为 91%）。新工艺基于新型催化剂、温和的反应条件、分离和纯化成本降低以及绿色试剂和溶剂的利用，大大提高了这种转化的可持续性。
