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与标准临床评估相比,药物诱导睡眠内镜检查显著改变了打鼾的管理计划。

Drug-induced sleep endoscopy changes snoring management plan very significantly compared to standard clinical evaluation.

机构信息

ENT Department, University Hospitals of Leuven, Leuven, Belgium.

出版信息

Eur Arch Otorhinolaryngol. 2014 May;271(5):1311-9. doi: 10.1007/s00405-013-2795-3. Epub 2013 Nov 7.

Abstract

Drug-induced sleep endoscopy (DISE) is a new tool in the work-up of patients with sleep-disordered breathing (SDB). We assessed the impact of DISE on the treatment plan of snoring patients. This is a single institution prospective longitudinal clinical trial. The setting is a private teaching hospital. A consecutive series of 100 snoring patients prospectively underwent a standardised questionnaire, clinical examination, rhinomanometry, allergy skin prick testing, DISE and polysomnography. Management plan before and after DISE evaluation was compared. In 61 patients (excluding 16 patients sent for continuous positive airway pressure, three patients refused sleep endoscopy and 20 were lost to follow-up), we compared the treatment plans. DISE showed single level airway collapse in 13 and multilevel collapse in 48 patients. The site of flutter did not add additional information as compared to the pattern and the location of the collapse. After DISE, the initial management plan changed in 41% of patients irrespective of the type of initial management plan. The only somewhat accurate initial treatment plan was uvulopalatopharyngoplasty (unchanged in 11/13 patients). Excluding moderate to severe obstructive sleep apnea patients DISE is an indispensable tool in treatment decision in all SDB patients. We suggest to simplify the protocol for DISE reporting.

摘要

药物诱导睡眠内镜检查(DISE)是睡眠呼吸障碍(SDB)患者检查的新工具。我们评估了 DISE 对打鼾患者治疗计划的影响。这是一项单中心前瞻性纵向临床试验。该研究地点为一家私立教学医院。连续 100 例打鼾患者前瞻性地接受了标准化问卷、临床检查、鼻阻力测量、过敏皮肤点刺试验、DISE 和多导睡眠图检查。比较了 DISE 评估前后的管理计划。在 61 例患者(不包括 16 例接受持续气道正压通气治疗的患者、3 例拒绝睡眠内镜检查的患者和 20 例失访的患者)中,我们比较了治疗计划。DISE 显示 13 例为单一水平气道塌陷,48 例为多水平塌陷。与塌陷模式和位置相比,振颤部位并未提供额外信息。DISE 后,41%的患者初始治疗计划发生改变,而与初始治疗计划的类型无关。唯一相对准确的初始治疗计划是悬雍垂腭咽成形术(13 例患者中未改变)。排除中重度阻塞性睡眠呼吸暂停患者后,DISE 是所有 SDB 患者治疗决策中不可或缺的工具。我们建议简化 DISE 报告的方案。

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