Leguay G, Lafargue P, Marbot P, Rassouly C, Droniou J, Kermarec J, Pernod J
Poumon Coeur. 1975;31(1):25-34.
The authors have dosed gamma glutamyl transpeptidase in 42 patients with primary bronchopulmonary cancer, of whom 14 had liver metastases. In these 14 patients the level of gamma glutamyl transpeptidase was always high, except in 1 case; while in the remaining lot, a moderate and mostly belated increase was noticed in only 32 percent of cases. The dosing of gamma glutamyl transpeptidase present some interest in the detection of liver metastases in primary bronchopulmonary cancers, specially when coupled with the dosing of alcaline phosphatase. Interpretation of results should take into account the existence of an associated liver-gall bladder involvement and of a recent surgical operation; both factors being capable of raising the level of gamma glutamyl transpeptidase.
作者对42例原发性支气管肺癌患者进行了γ-谷氨酰转肽酶检测,其中14例有肝转移。在这14例患者中,除1例之外,γ-谷氨酰转肽酶水平始终较高;而在其余患者中,仅32%的病例出现中度且大多延迟的升高。γ-谷氨酰转肽酶检测在原发性支气管肺癌肝转移的检测中具有一定意义,特别是与碱性磷酸酶检测相结合时。结果解读应考虑是否存在相关的肝胆受累以及近期是否进行过手术;这两个因素都可能导致γ-谷氨酰转肽酶水平升高。