Cameron Anne P, Haraway Allen McNeil
Department of Urology, Division of Neurourology and Pelvic Floor Reconstruction, University of Michigan Health System, Ann Arbor, MI, USA.
Open Access J Urol. 2011 Jun 17;3:109-20. doi: 10.2147/OAJU.S10541.
To review the literature on the surgical and nonsurgical treatment options for stress urinary incontinence in women, focusing exclusively on randomized clinical trials and high quality meta-analyses.
A computer-aided and manual search for published randomized controlled trials and high quality meta-analyses investigating both conservative and surgical treatment options for stress urinary incontinence. In the case of a treatment that is not studied in these formats large case series have been used.
Articles were reviewed and the results summarized on pelvic floor physical therapy, pharmacotherapy, bulking agents, and surgery (open and minimally invasive).
There are numerous high quality studies in the literature. It can be difficult to make definitive conclusions on the most appropriate treatment options due to the variability in the outcomes used to define success in these articles. There is also a dire lack of studies evaluating and comparing the surgical options for patients with intrinsic sphincter deficiency.
回顾关于女性压力性尿失禁手术及非手术治疗方案的文献,仅聚焦于随机临床试验和高质量的荟萃分析。
通过计算机辅助及人工检索已发表的随机对照试验和高质量荟萃分析,这些研究调查了压力性尿失禁的保守及手术治疗方案。对于未以这些形式进行研究的治疗方法,则使用了大型病例系列。
对文章进行了综述,并总结了盆底物理治疗、药物治疗、填充剂及手术(开放手术和微创手术)的结果。
文献中有大量高质量研究。由于这些文章中用于定义成功的结果存在差异,因此很难就最合适的治疗方案得出明确结论。此外,严重缺乏评估和比较内在括约肌缺陷患者手术选择的研究。