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[疑似良性卵巢肿瘤的超声诊断]

[Sonographic diagnosis of presumed benign ovarian tumors].

作者信息

Marret H, Cayrol M

机构信息

Pôle de gynécologie, obstétrique, médecine fœtale et reproduction humaine, hôpital Bretonneau, 37044 Tours cedex 1, France.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 2013 Dec;42(8):730-43. doi: 10.1016/j.jgyn.2013.09.028. Epub 2013 Nov 5.

Abstract

To discriminate ovarian lesions is of particular importance in gynecological practice. Two main problems need answers: discrimination of benign and malignant adnexal masses and choice of the appropriate surgical treatment if necessary. Nearly 2% of the adnexal masses are ovarian carcinomas or borderline tumors. It is now, well established that ultrasonography is the gold standard for ovarian cyst diagnosis. The purpose of this data was to review the literature and to establish, with the evidence base medicine model, which parameters and existing diagnostic models using ultrasound and Doppler perform best in the evaluation of adnexal masses. Transvaginal sonography has demonstrated considerable advantage over conventional transabdominal sonography. However, transparietal sonography is still useful in large tumors. Definition of the nomenclature and classification was done and should be used. Unilocular ovarian cyst characterization seems easy using sonography and Doppler. In front of complication, discrimination of such functional cyst may be difficult but spontaneous regression confirms usually the expectative management. Dermoid cysts and endometriomas seem to be easier to discriminate from other adnexal masses. Ultrasound and morphologic parameters have a sensitivity of about 90% and a specificity of 80%; that makes this exam the gold standard for ovarian masses diagnosis. Only 50% of ovarian masses are characterized by sonography. Scoring systems help to differentiate benign from malignant masses (sensitivity of about 90%). Logistic regression and models are good methods especially for LR1 and 2 and RMI and may be useful for malignancy prediction but are difficult to use in current practice. Expert diagnosis is a subjective but most important performing parameter. Any suspicious ovarian mass or not easily diagnosed mass requires sonography by an expert, which can first use all the techniques and the different parameters to discriminate benign and malignant tumors. An explicit report will help the physician to define the right attitude for an appropriate management. Six to 16% of adnexial masses are complex or not classified and will result in MRI prescription or surgery.

摘要

在妇科实践中,鉴别卵巢病变尤为重要。有两个主要问题需要解答:鉴别附件包块的良恶性以及必要时选择合适的手术治疗方式。近2%的附件包块为卵巢癌或交界性肿瘤。目前,超声检查已被公认为卵巢囊肿诊断的金标准。本数据的目的是回顾文献,并依据循证医学模式确定在评估附件包块时,使用超声和多普勒的哪些参数及现有诊断模型表现最佳。经阴道超声检查已显示出相较于传统经腹超声检查具有显著优势。然而,经腹超声检查在较大肿瘤中仍有用处。已对术语和分类进行了定义并应予以使用。使用超声和多普勒对单房卵巢囊肿进行特征描述似乎较为容易。面对并发症时,鉴别此类功能性囊肿可能会很困难,但自发消退通常可证实采取期待性处理的合理性。皮样囊肿和子宫内膜异位症似乎比其他附件包块更容易鉴别。超声和形态学参数的敏感性约为90%,特异性为80%;这使得该检查成为卵巢包块诊断的金标准。仅有50%的卵巢包块可通过超声检查进行特征描述。评分系统有助于区分良性和恶性包块(敏感性约为90%)。逻辑回归和模型是很好的方法,尤其是对于LR1和2以及RMI,可能对恶性肿瘤预测有用,但在当前实践中难以应用。专家诊断是一个主观但最重要的执行参数。任何可疑的卵巢包块或不易诊断的包块都需要由专家进行超声检查,专家可首先使用所有技术和不同参数来鉴别良性和恶性肿瘤。一份明确的报告将有助于医生确定正确的处理态度以进行恰当的管理。6%至16%的附件包块为复杂或未分类的,这将导致进行MRI检查或手术。

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