Engel S, Diezel W, Sönnichsen N
Acta Derm Venereol. 1985;65(6):484-8.
Rabbits were immunized using isolated and dissolved specific immune complexes obtained from patients suffering from early syphilis. After immunization the rabbits were infected intradermally with living Treponema pallidum. Some of them did not develop lesions at the infection sites. In comparison to controls there was a delayed and reduced production of antibodies. The effect of immunization may be induced by a treponemal protein antigen as a constituent of the specific immune complexes.
用从早期梅毒患者身上分离并溶解得到的特异性免疫复合物对兔子进行免疫。免疫后，给兔子皮内接种活的梅毒螺旋体。其中一些兔子在感染部位未出现病变。与对照组相比，抗体产生延迟且减少。免疫效果可能是由作为特异性免疫复合物组成成分的梅毒螺旋体蛋白抗原诱导产生的。
