Sahlgrenska University Hospital, Gothenburg, Sweden.
Epilepsy Behav. 2013 Dec;29(3):565-70. doi: 10.1016/j.yebeh.2013.10.012. Epub 2013 Nov 5.
Intelligence before and two years after epilepsy surgery was assessed in 94 children and adolescents and related to preoperative IQ and seizure outcome. The median full-scale IQ was 70 before and two years after surgery. The proportion with a higher or unchanged postoperative IQ was 24 of 49 (49%) of those with an IQ of 70 and more before surgery, nine of 17 (53%) of those with an IQ of 50-69, and ten of 28 (36%) of those with an IQ of less than 50. A significant difference was found between the 47 individuals who became seizure-free and the 47 with persisting seizures, as 60% of the seizure-free children had a higher or unchanged IQ compared with 32% of the 47 who were not seizure-free. The cognitive outcome of children with intellectual disabilities was as good as that of children with average IQ. Thus, they should not be excluded from epilepsy surgery on the basis of low intellectual level.
对 94 名儿童和青少年进行癫痫手术后 2 年的术前智力评估，并将其与术前智商和癫痫发作结果相关联。手术前的全量表智商中位数为 70，手术后 2 年为 70。术前智商为 70 及以上的 49 名患者中，有 24 名（49%）术后智商升高或不变，术前智商为 50-69 的 17 名患者中，有 9 名（53%）术后智商升高或不变，术前智商低于 50 的 28 名患者中，有 10 名（36%）术后智商升高或不变。在 47 名无癫痫发作的患者和 47 名持续癫痫发作的患者之间存在显著差异，因为 60%的无癫痫发作患者的智商升高或不变，而 47 名未无癫痫发作的患者中，只有 32%的患者的智商升高或不变。智力障碍儿童的认知结果与平均智商儿童一样好。因此，不应根据智力水平低而将他们排除在癫痫手术之外。
