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心房利钠因子。在大鼠心脏特定心房颗粒中的免疫组织化学定位。

Atrial natriuretic factor. Immunohistochemical localization in the specific atrial granules of the rat heart.

作者信息

Vuolteenaho O, Arjamaa O, Järvinen M, Rinne A

出版信息

Acta Histochem. 1985;77(2):199-203. doi: 10.1016/S0065-1281(85)80085-4.

Abstract

Atrial natriuretic peptides (atrial natriuretic factor, ANF) were localized in rat heart atria using immunohistochemical methods. A large number of heavily stained granules were detected mainly in the vicinity of the nuclei of the atrial muscle cells, but some staining was also present in granules located near the sarcolemma. The results show that the specific atrial granules are loaded with atrial natriuretic peptides.

摘要

采用免疫组化方法将心房利钠肽(心房利钠因子,ANF)定位在大鼠心脏心房中。主要在心房肌细胞核附近检测到大量深染颗粒,但在肌膜附近的颗粒中也有一些染色。结果表明,特定的心房颗粒中含有心房利钠肽。

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